Biomarkers in Drug formulation

Drug formulation also covers the surrogate end points in the use of biomarkers and patient selection or companion diagnostics and provides insights into clinical biomarker discovery and biomarker development or validation with regulatory implications. Biomarker use can improve pharmaceutical development efficiency by helping to select patients most appropriate for treatment using a given mechanism, optimize dose selection, and provide earlier confidence in accelerating or discontinuing compounds in clinical development.

Biomarker in Drug discovery

 

Biomarker in Drug Design

 

Dose selection in Biomarker

 

Biomarkers of Toxicity & Pharmacology

 

Biomarkers in dose selection

 

Evaluation of dose respons

 

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